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“This is an interesting article that already confirms what cosmetic surgeons have seen in practice for years. Combination therapy is always more effective thAn any modality alone.”

–Dr Rubbani

Fillers Last Longer With Botox

February 02, 2016 By Lisette Hilton

Chemodenervation, using botulinum neurotoxin-A, prolongs the lasting effects of hyaluronic acid (HA) fillers by reducing muscle activity in the treated area, according to a new study.

Aesthetic physicians have been known to use HA fillers in combination with Botox (Allergan) to temporarily reduce muscle activity and prolong filler life. Turkish researchers used an animal model to more objectively demonstrate the approach.
Another New York City plastic surgeon, David Shafer, M.D., says the new study gives objective evidence to observations that plastic surgeons see every day in clinical practice.

“Combination treatment (chemodenervation with Botox plus hyaluronic acid fillers, such as Juvéderm or Restylane) tends to give a prolonged and enhanced effect when compared to filler alone,” Dr. Shafer says. “This method of study allows for direct comparison and control in the same model. Translation to clinical practice is straightforward as both products are commonly used in combination already.